# The CRISPR Bottleneck Moved. Now Comes the Hard Part.

- slug: the-crispr-bottleneck-moved-now-comes-the-hard-part
- date: 2026-04-15
- category: Biotech & Life Sciences

The CRISPR delivery bottleneck has officially moved. Al3Cas12f RKK is small enough for AAV and efficient enough in cells — the hard part now is whether it works inside a living animal.

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