# Karyopharm's Spleen Win Masks Symptom Failure in Myelofibrosis Study

- slug: karyopharms-spleen-win-masks-symptom-failure-in-myelofibrosis-study
- date: 2026-03-24
- category: Biotech & Life Sciences

Two biotech companies — Karyopharm and Rezolute — two very different stumbles toward the same regulator, and an FDA that may be rewriting the rulebook on what counts as enough evidence to approve a drug.

Karyopharm Therapeutics on Monday reported topline results from the Phase 3 SENTRY trial of ...

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