# Base editing cuts toxic protein 84% in AATD trial, FDA backs accelerated approval

- slug: base-editing-cuts-toxic-protein-84-in-aatd-trial-fda-backs-accelerated-approval
- date: 2026-03-25
- category: Biotech & Life Sciences

For people living with alpha-1 antitrypsin deficiency, the disease is a slow-motion double insult: the lungs erode without protection, and the liver accumulates a misfolded protein it cannot clear.

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